Black and Asian patients have increased risk of severe COVID-19 at different stages of the disease

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Black patients are at increased risk of being hospitalized for COVID-19, while Asian patients are at increased risk of dying of COVID-19 in hospital compared to white patients, according to a study.

The data analysis published today in EClinicalMedicine, conducted by researchers at King’s College London with support from the NIHR Guy and St. Thomas Biomedical Research Center and the British Heart Foundation (BHF), examines the relationship between ethnic background and the SARS-CoV virus – 2nd

The study confirms that ethnic minority patients bear a higher burden of disease than white patients and that black and Asian patients are affected at different stages of the disease.

Professor Ajay Shah, BHF Professor of Cardiology at King’s College London and Consultant Cardiologist at King’s College Hospital, said: “The finding that black and Asian patients are affected in very different ways and that they are at significant risk even after adapting to deprivation and long-term The term health status is suspicious. This strongly suggests that other factors, possibly biological, are important and that we may need different treatment strategies for different ethnic groups. In Asian patients, it may be how to manage life-threatening complications. “

Professor Chris Whitty, Chief Medical Officer for England and Head of the NIHR, said: “It is now clear that people from black and ethnic minorities are more affected by COVID-19. This NIHR-supported study shows how different groups are affected who provide vital information to help healthcare professionals provide the best possible care to ethnic minority patients. “

The study analyzed data from 1,827 adult patients admitted to King’s College Hospital in south east London between March 1 and June 2, 2020, with a primary diagnosis of COVID-19.

The researchers analyzed mortality in this group and compared a subset of 872 enrolled patients from central south-east London to 3,488 matched controls in the same region to determine how ethnic background is linked to the need for hospitalization for serious illness. Of these 872 enrolled patients, 48.1% were black, 33.7% white, 12.6% mixed, and 5.6% Asian.

The analysis found that black and mixed ethnicity patients were three times more likely to be hospitalized after being infected with COVID-19 than white residents of the same area’s inner city. This is only partially explained by comorbidities and deprivation as an adaptation to these factors. Black patients still have a 2.2 to 2.7 times higher risk of admission. However, the hospital survival of these patients was not significantly different from that of the white patients.

In contrast, Asian patients were no higher risk of being hospitalized with COVID-19 than white patients, but their hospital mortality rate and ICU need to be admitted were higher than the other groups.

The researchers observed that the ethnic minority patients were 10 to 15 years younger than the white patients and had a higher prevalence of comorbidities, particularly diabetes.

The study suggests that while comorbidities and socio-economic factors contribute to the impact of COVID-19 on minority communities, other factors, such as biological factors that affect different subgroups in different ways, may play an important role.

The results of this study are likely applicable to all of London and similar UK cities, but more research is needed to extrapolate them to multiethnic populations in other countries.

Dr. Sonya Babu-Narayan, Associate Medical Director at the British Heart Foundation, said, “This study provides further evidence that COVID-19 disproportionately affects those whose ethnic background is a minority as seen around the world. Why Coronavirus hit people with ethnic minority backgrounds harder and how to mitigate that has been complex to deal with. “

She continued, “People from Black, Asian, and other ethnic minorities are more likely to have cardiovascular risk factors such as high blood pressure and diabetes and are more exposed to socio-economic disadvantages. However, this study shows that the worst effects of COVID-19 are there, even after considering them Research is now needed to evaluate how other structural and behavioral factors may contribute including occupation, access to health news and care, and differences in patient travel once people reach the hospital. As we see COVID-19 in the UK cases are re-emerging. We urgently need to address these differences. ”

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More information:
EClinicalMedicine, DOI: 10.1016 / j.eclinm.2020.100574 Provided by King’s College London

Quote: Black and Asian patients are at increased risk of severe COVID-19 at various stages of the disease (2020, October 9), accessed October 9, 2020 from asian-patients-severe-covid-.html

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